| | generic ativan reviews generic ativan side effects - In the fall of 1997, fenfluramine (the fen half of the popular fen-phen drug combination) and Redux (dexfenfluramine) were recalled after the drugs were linked to potentially fatal heart valve abnormalities. In November of 1997, only a few months after the withdrawal of fenfluramine and Redux, the Federal Drug Administration (FDA) approved Meridia. Meridia is a class of drug known as monoamine (serotonin and norepinephrine) re-uptake inhibitors. It falls in the same class of many anti- depressants such as Prozac. Serotonin is a chemical released in the brain after you have eaten a meal, which makes you feel full. When a nerve impulse reaches the end of the nerve (the nerve terminal), the impulse causes the release of chemicals called neurotransmitters. The neurotransmitters are released in the space between the two adjacent neurons, this region is called the synaptic cleft. Usually once the neurotransmitters have bound to their receptors (the neurotransmitter and the receptor fit like a lock and a key) on the adjacent nerve, transport proteins work to reabsorb the extra neurotransmitter back into the nerve terminal so that they can be reused. However, Meridia acts to inhibit the reabsorption of serotonin so the that signal lasts longer, thus giving the sensation that you are full for a longer period of time. This method is thought to effectively reduce the caloric intake of an obese individual due to appetite suppression. For an informational video on the mechanism of action for Meridia visit the world wide web at www.4meridia.com/hcprof/fma.htm. How is Meridia Different from the Recalled Drugs? - http://www.bigwhitemonkeyamps.com/ativan.html generic ambien online cheap generic ambien online pharmacy - Although Meridia and fenfluramine have similar mechanisms of action (they both affect serotonin), fenfluramine boosts the levels of serotonin into the blood stream. This increase in the levels of serotonin is believed to have caused the heart valve damage seen in some patients. Essentially the difference between the two drugs is that Meridia is more localized, whereas fenfluramine has a systemic effect. Because of this difference, researchers believe that Meridia will not be linked with heart valve damage. As stated by Lawrence Cheskin, M.D., director of the Johns Hopkins Weight Management Center in Baltimore, "Meridia bypasses the heart and acts directly on the brainｿｽs appetite control center. Meridia maintains serotonin levels in the brain, thereby curbing some carbohydrate cravings (Brietzke, 90)". Carbohydrates boost levels of serotonin in the brain, and this impacts appetite and mood so when your brain is running low on the chemical, it tells you to refuel. Meridia keeps serotonin levels elevated, short-circuiting these mentally fueled cravings. The drug also boosts adrenaline levels, curbing overall appetite. Side Effects - http://www.bigwhitemonkeyamps.com/ambien.html adderall without prescription forum adderall without prescription legal - Though Meridia may be safer than other anti- obesity drugs, it still warrants caution. The most troubling side effects include increase in blood pressure, heart rate, and abnormal heart rhythms (arrythmias) seen in some participants during clinical trials. However, most of these side effects were observed in participants who took large doses (more than 15 mg) of the drug (Portyansky, 23). Blood pressure elevations were controlled in these trials with dose adjustments . Those who do have high blood pressure to begin with are urged to weigh the benefits and risks of taking this drug. Meridiaｿｽs labeling recommendations calls for blood pressure and pulse measurements prior to therapy initiation and regular monitoring thereafter for all patients. For more information on the increase in blood pressure and heart rate go to www.4meridia.com/hcprof/fsa.htm on the world wide web. The most commonly reported side effects include dry mouth, headache, constipation, and insomnia, "but people seem to find these effects pretty tolerable", according to Cornell Medical Centerｿｽs Dr. Louis Aronne (Anonymous, 98). Who Should Take Meridia? - http://www.bigwhitemonkeyamps.com/adderall.html buy phentermine 37.5 diet pills buy phentermine 37.5 from canada - Meridia is targeted for the seriously obese and not for those who are looking to lose a few pounds. Linda Mayer, director of communications at Knoll, states, "This is serious medicine, and it is only for certain people. In the past, there has been too much emphasis on cosmetic use of obesity drugs. Weｿｽre focusing on the health benefits. It is not about how you look but instead about how your health will improve if you lose weight (Fentress, 33-34)". This drug is recommended only for obese patients with an initial body mass index (BMI) greater or equal to 30 ( a person who is 5ｿｽ5" and weight 180 pounds), or a BMI of 27 in the presence of other risk factors, such as diabetes, hypertension, arthritis, sleep apnea, or dyslipidemia (low HDL and high triglycerides) (Fentress, 33-34). BMI is a measurement based on height and weight as they relate to body fat. It can be used to determine how much risk people have of developing certain health problems because of their weight. Someone with a BMI of 27 is approximately 20% overweight. The higher the BMI, the greater the risk a person has to develop additional health problems. To calculate your BMI you can go to www.4meridia.com/consumer/archive/bmi.cfm. Knollｿｽs web site (www.4meridia.com/consumer/3200.html#5) states that the drug should not be used by patients who: - http://www.bigwhitemonkeyamps.com/adipex.html librium medication librium medication alcohol - ﾂｷ take drugs called monoamine oxidase inhibitors (MAOIｿｽs), which are used for depression, Parkinsonｿｽs Disease, and other disorders. This is very important because serious, sometimes even fatal, reactions can occur if Meridia is taken at the same time MAOIｿｽs are taken; ﾂｷ take other weight loss medicines that act on the brain, such as phentermine. This includes prescription drugs, over- the- counter medicines, and herbal products; - http://www.bigwhitemonkeyamps.com/librium.html
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