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| [url=http://buycialisonline.co.uk/][img]http://buycialisonline.co.uk/buycialisonline.png[/img][/url] MECHANISM OF ACTION裏Does not directly cause penile erections, but affects the response to sexual stimulation. The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in the corpus cavernosum during sexual stimulation. NO then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation and inflow of blood to the corpus cavernosum. Cialis (Tadalafil) enhances the effect of NO by inhibiting phosphodiesterase type 5 (PDE-5), which is responsible for degradation of cGMP in the corpus cavernosum; when sexual stimulation causes local release of NO, inhibition of PDE-5 by tadalafil causes increased levels of cGMP in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. At recommended doses, it has no effect in the absence of sexual stimulation. [url=http://buycialisonline.co.uk/]buy cialis online uk[/url] [url=http://buylevitra.net/][img]http://buylevitra.net/buylevitra.png[/img][/url] Inform prescriber of all other medications you are taking; serious side effects can result when Levitra (vardenafil) is used with nitrates and some other medications. Do not combine vardenafil with other approaches to treating erectile dysfunction without consulting prescriber. Note: Levitra (Vardenafil) provides no protection against sexually-transmitted diseases, including HIV. You may experience headache, flushing, or abnormal vision (color changes, blurred or increased sensitivity to light); use caution when driving at night or in poorly lit environments. Stop using and notify prescriber immediately in case of vision loss. Report immediately acute allergic reactions; chest pain or palpitations; persistent dizziness; sign of urinary tract infection; skin rash; difficulty breathing; genital swelling; or other adverse reactions. If erection lasts >4 hours, contact prescriber immediately; permanent damage to the penis can occur. [url=http://buylevitra.net/]cheap levitra[/url] |