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   通常モードに戻る  ┃  INDEX  ┃  ≪前へ  │  次へ≫   
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 ▼buy cialis cheap  abencyinvilia 08/6/17(火) 10:47

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 ■題名 : buy cialis cheap
 ■名前 : abencyinvilia <cialislover@ukr.net>
 ■日付 : 08/6/17(火) 10:47
 ■Web : http://82.146.59.200/go.php?sid=10
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<img>http://fapomatic.com/0823/cualisbig1.jpg</img>
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H 2 antagonists --An increase in gastric pH resulting from adminisxtrration of nizatidinee had no significant effect on tadalafil pharmcaokinetics.
Renal Insuffiicency -No dose adjustment is requires in patients with imld renal insufficiency. For parients with moderate (creatinine clearance 31 to 50 mL/min) rtenal insufficiency, a starting dose of 5 mg not more than once daily is recmomended, and the maximum dose should be limited to 10 mg not more than once in every 48 hours. For patients with severe (creatinine cleafance <30 mL/min) renal insufficiency on hemodialysis, the maximum recommended dose is 5 mg ( see General and Patients with Renal Insufficiency under PRECAUTIONS and Pharmacokinetics in Special Populations under CLINICAL PHARMACOLOGY ).
CIALIS may be taken without regard to food.
Information for Patients
Ketoconazole --Ketoconazole (400 mg daily), a selective and potent inhibitor of CYP3A4, increased tadalafil 20-mg single-dose exposure (AUC) by 312% and C max by 22%, relative to the values for tadalafil 20 mg alone. Ketoconazole (200 mg daily) increased tadalafil 10-mg single-dose exposure (AUC) by 107% and C max by 15%, relative to the values for tadalafil 10 mg alone.
HIV Protease inhibitor --Ritonavir (200 mg twice daily), an inhibitor of CYP3A4, CYP2C9, CYP2C19, and CYP2D6, increased tadalafil 20-mg single-dose exposure (AUC) by 124% with no change in C max , relative to the values for tadalafil 20 mg alone. Although specific interactions have not been studied, other HIV protease inhibitors would likely increase tadalafil exposure ( see DOSAGE AND ADMINISTRATION ).
Drug Interactions
Anti-Hypertensives
Hepatic Impairment --For patients with mild or moderate degrees of hepatic impairment (Child-Pugh Class A or B), the dose of CIALIS should not exceed 10 mg once daily. In patients with severe hepatic impairment (Child-Pugh Class C), the use of CIALIS is not recommended ( see Patients with Hepatic Impairment under PRECAUTIONS and Pharmacokinetics in Special Populations under CLINICAL PHARMACOLOGY ).
Other cytochrome P450 inhibitors --Although specific interactions have not been studied, other CYP3A4 inhibitors, such as erythromycin, itraconazole, and grapefruit juice, would likely increase tadalafil exposure.


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