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It is used in addition to diet and exercise to lower blood sugar in adults who cannot manage with diet, exercise, or diabetic medications alone. It may be used with other diabetes medicines. How to use Use Prandin as directed by your doctor. Check the label on the medicine for exact dosing instructions. Take Prandin by mouth at least 15 to 30 minutes before each meal. If you skip a meal, do not take the dose for the skipped meal. If you add an extra meal, take an extra dose with that meal. Drug Class and Mechanism Prandin is a meglitinide antidiabetic. It works to lower blood glucose (sugar) by stimulating the release of insulin from the pancreas gland. Prandin does not work in type 1 (insulin-dependent) diabetes, because in this condition the pancreas gland is not capable of making or releasing insulin. Missed Dose If you miss a dose of Prandin , skip the missed dose and go back to your regular dosing schedule. 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